Chemistry data
- Class
- triple incretin receptor agonist (GLP-1/GIP/glucagon)
- Sequence
- Not publicly disclosed (proprietary Eli Lilly peptide)
- Half-life
- approximately 6 days (enabling once-weekly dosing)
- Routes
- subcutaneous
- Studied doses
- subcutaneous 1 mg, 4 mg, 8 mg, or 12 mg once weekly · subcutaneous 0.5 mg to 12 mg once weekly
Stato Normativo
- Stati Uniti
- investigational
- Unione Europea
- research_only
- Regno Unito
- research_only
Come funziona
- GLP-1 receptor agonism enhancing insulin secretion, suppressing glucagon release, and promoting satiety through central nervous system pathways
- GIP receptor agonism augmenting insulinotropic effects and potentially improving lipid metabolism and adipose tissue function
- Glucagon receptor agonism stimulating hepatic fatty acid oxidation, increasing energy expenditure, and promoting lipolysis
- Synergistic triple receptor activation producing greater weight loss than single or dual agonism through complementary metabolic pathways
Risultati della ricerca
- fat-loss clinical
- metabolic-health clinical
- liver-health clinical
- glucose-regulation clinical
Contesto di dosaggio
-
- Vie di Somministrazione
- subcutaneous
- Intervallo
- 1 mg, 4 mg, 8 mg, or 12 mg once weekly
Phase 2 clinical trials for obesity (escalation from 0.5 mg to target dose over 4-8 weeks)
-
- Vie di Somministrazione
- subcutaneous
- Intervallo
- 0.5 mg to 12 mg once weekly
Phase 2 clinical trials for type 2 diabetes (various escalation regimens)
🧮 Reconstitution Calculator
Determine exactly how much bacteriostatic water to add and how many units to draw for your target dose.
Effetti collaterali: contesto di ricerca
- nausea (most common, typically mild to moderate)
- diarrhea
- vomiting
- constipation
- decreased appetite
- abdominal pain
- injection site reactions
Il riassunto completo della ricerca arriverà presto. Nel frattempo, consulta i dati scientifici e i riferimenti PubMed sopra.
Pagine Correlate
- semaglutide
- tirzepatide
- retatrutide
- retatrutide
- retatrutide
- retatrutide
- Retatrutide vs GHK-Cu
Comparison
- Retatrutide vs Semaglutide
Comparison
- Retatrutide vs Tirzepatide
Comparison
- Retatrutide vs Tesamorelin
Comparison