Chemistry data
- Class
- growth hormone secretagogue (GHS) / ghrelin receptor agonist
- Molecular weight
- 872.44 g/mol
- Sequence
- His-D-Trp-Ala-Trp-D-Phe-Lys-NH2
- Half-life
- approximately 2.5 hours (elimination phase)
- Routes
- subcutaneous · intramuscular
- Studied doses
- subcutaneous 100–300 mcg per injection, 1–3x daily
Status Regulacyjny
- Stany Zjednoczone
- research_only
- Unia Europejska
- research_only
- Wielka Brytania
- research_only
Jak to działa
- Potent GH release via ghrelin receptor (GHS-R1a) agonism — dual pituitary and hypothalamic site of action
- Strongest appetite stimulation (orexigenic effect) among all GHRPs via ghrelin mimicry
- Modest cortisol and prolactin elevation at higher doses — broader hormonal footprint than selective successors
Wyniki badań
- appetite-stimulation preclinical
- muscle-growth preclinical
- gastrointestinal-motility preclinical
Kontekst dawkowania
-
- Drogi Podania
- subcutaneous
- Zakres
- 100–300 mcg per injection, 1–3x daily
anecdotal human use; animal study doses vary (typically 200 mcg/kg in mice)
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Efekty uboczne: kontekst badań
- pronounced hunger (expected pharmacological effect)
- mild headache (anecdotal)
- flushing post-injection (anecdotal)
- water retention at high doses (anecdotal)
Pełne podsumowanie badań wkrótce. Tymczasem zajrzyj do danych naukowych i referencji PubMed powyżej.